Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1997 May;5(5):205-8.
doi: 10.1016/S0966-842X(97)01035-4.

Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori?

A Covacci  1 , S Falkow, D E Berg, R Rappuoli
Affiliations
Review

Did the inheritance of a pathogenicity island modify the virulence of Helicobacter pylori?

A Covacci et al. Trends Microbiol. 1997 May.

Abstract

Strains of Helicobacter pylori from patients with peptic ulcer disease and gastric cancer contain a 40-kb fragment of DNA that is not present in isolates from carriers with asymptomatic infections. The discovery of the cag pathogenicity island suggests that virulence has evolved by quantum leaps through the inheritance of one or more DNA insertions.

PubMed Disclaimer

Comment in

Publication types

LinkOut - more resources