Pathogenesis of endometriosis
- PMID: 9163764
- DOI: 10.1016/s0889-8545(05)70301-6
Pathogenesis of endometriosis
Abstract
This article reviews the pathogenesis of endometriosis, which involves retrograde dissemination of endometrium and/or development in situ by metaplasia, and there is evidence suggesting that genetic and hormonal factors may play a role. There is also substantial evidence that immunologic factors, namely peritoneal macrophages, T cells, natural killer cells, and soluble products secreted by these cells, are involved in the pathogenesis of endometriosis.
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