Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1997 Jun;65(6):2457-61.
doi: 10.1128/iai.65.6.2457-2461.1997.

Infection of BALB/c mice with the filarial nematode Litomosoides sigmodontis: role of CD4+ T cells in controlling larval development

K M Al-Qaoud  1 , A Taubert, H Zahner, B Fleischer, A Hoerauf
Affiliations

Infection of BALB/c mice with the filarial nematode Litomosoides sigmodontis: role of CD4+ T cells in controlling larval development

K M Al-Qaoud et al. Infect Immun. 1997 Jun.

Abstract

Litomosoides sigmodontis is the only filaria which develops from infective larvae into adults in immunocompetent laboratory mice. Depletion of CD4+ T cells from infected BALB/c mice resulted in worm and microfilarial burdens significantly higher than those of infected controls. Th2 cytokines, eosinophilia, and immunoglobulin E, which were strongly induced in infected controls, were diminished in CD4-depleted mice.

PubMed Disclaimer

References

    1. J Parasitol. 1992 Jun;78(3):447-53 - PubMed
    1. Exp Parasitol. 1994 Jun;78(4):352-60 - PubMed
    1. J Parasitol. 1983 Jun;69(3):478-85 - PubMed
    1. Parasitology. 1983 Feb;86 (Pt 1):11-8 - PubMed
    1. Z Parasitenkd. 1986;72(6):789-804 - PubMed

Publication types