[Effect of an antioxidant (ubiquinone Q-9) and chronic low-dose irradiation on rat chromatin structure and T-lymphocyte proliferation]
[Article in
Russian]
- PMID: 9172692
Item in Clipboard
[Effect of an antioxidant (ubiquinone Q-9) and chronic low-dose irradiation on rat chromatin structure and T-lymphocyte proliferation]
[Article in
Russian]
Biofizika.
1997 Mar-Apr.
Abstract
We have demonstrated the protective effect of natural antioxidant coenzyme Q-9 on the T-cell proliferative capacity and chromosomal DNA state under low dose chronic irradiation. The DNA-staining fluorescent dye Hoechst-33258 and acridine orange were to observed the nuclear morphology changes in T-lymphocytes. Ubiquinone diet partially restored the decreasing in immune response and the luminescence intensity of DNA-Hoechst-33258 complex in T-cells of low dose irradiated rats.
Similar articles
-
Early and long-term effects of chronic low-dose radiation and coenzyme Q diet on the proliferation of rat spleen T cells.Indian J Biochem Biophys. 1998 Apr;35(2):103-7. Indian J Biochem Biophys. 1998. PMID: 9753869
-
[Fluorescent analysis of irradiation-induced changes in chromatin state].Biofizika. 2001 Jul-Aug;46(4):676-83. Biofizika. 2001. PMID: 11558379 Russian.
-
Immune functions of spleen lymphocytes of rats subjected to chronic irradiation and antioxidant (ubiquinone Q-9) diet.Int J Radiat Biol. 1995 Apr;67(4):469-76. doi: 10.1080/09553009514550541. Int J Radiat Biol. 1995. PMID: 7738411
-
[Effects of ubiquinone-9 on lipids of nuclei and chromatin of the rat liver under continuous irradiation].Biull Eksp Biol Med. 1992 Mar;113(3):253-4. Biull Eksp Biol Med. 1992. PMID: 1421218 Russian.
-
Is coenzyme Q a key factor in aging?Mech Ageing Dev. 2010 Apr;131(4):225-35. doi: 10.1016/j.mad.2010.02.003. Epub 2010 Mar 1. Mech Ageing Dev. 2010. PMID: 20193705 Review.
MeSH terms
Substances
LinkOut - more resources
Medical