[Poems syndrome: a case report]

Abstract

Introduction: The Poems syndrome (polyneuropathy, organomegaly, endocrinopathy, monoclonal gammapathy and skin changes) is an uncommon multisystemic disorder. Usually it is a manifestation of a type of myeloma of which the chief characteristic is the presence of osteosclerotic lesions, classically seen radiologically to be single or multiple. Nowadays, not only is Poems considered to be a manifestation of osteosclerotic myeloma, but may also be seen associated with other plasma cell dyscrasias.

Clinical case: We present a case of Poems syndrome secondary to a plasmocytoma of the dorsal vertebral column in a 32 year old male negro. Initially he had sensori-motor polyneuropathy associated with other features characteristic of the syndrome (organomegaly, IgA monoclonal gammapathy and skin changes). Later he also showed signs attributed to a compressive lesion of the dorsal spinal medulla. An unusual finding in this patient was that the bony lesion was predominantly osteoclytic.

Conclusions: We briefly review the syndrome and comment on the diagnosis.