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. 1997 Mar;36(3):401-3.
doi: 10.1016/s0028-3908(97)00014-2.

Pharmacological characterization of synaptic transmission through mGluRs in rat cerebellar slices

A M Batchelor  1 , T Knöpfel, F Gasparini, J Garthwaite
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Pharmacological characterization of synaptic transmission through mGluRs in rat cerebellar slices

A M Batchelor et al. Neuropharmacology. 1997 Mar.

Abstract

The mGluR-mediated EPSP at parallel fibre-Purkinje cell synapses in the cerebellum was blocked concentration-dependently and reversibly by antagonists acting selectively on group-I mGluRs but not by an inhibitor of group-III receptors. The results provide pharmacological evidence that the receptor type responsible for the mGluR-EPSP is mGluR1.

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