[A method for selecting drugs that affect the rheological properties of the blood in vitro]
[Article in
Russian]
- PMID: 9181877
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[A method for selecting drugs that affect the rheological properties of the blood in vitro]
[Article in
Russian]
Eksp Klin Farmakol.
1996 Nov-Dec.
Abstract
For the selection of compounds affecting the hemorrheologic status a method for reproducing disorders of blood rheologic properties in vitro was developed. It consists in 60-min incubation of blood at 42 degrees C. The hemorrheologic effect of quercetin under such conditions was studied and a dependence of the effect of quercetin on blood viscosity and red cell aggregation on the drug concentration was revealed.
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