[Characteristics of nucleic acids excreted by non-stimulated normal human lymphocytes]

Abstract

Unstimulated human blood lymphocytes have been shown to release in vitro a complex containing DNA and RNA. These nucleic acids are composed of newly synthesized material and appear to be released according to a homeostatic mechanism. Extracellular synthesis of the released DNA has been demonstrated by using a nearest neighbor analysis technique. The characteristics of the extracellular nucleic acids have been investigated biochemically and by electron microscopy.