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. 1997 Jun;179(12):4075-9.
doi: 10.1128/jb.179.12.4075-4079.1997.

A signal transducer for aerotaxis in Escherichia coli

S I Bibikov  1 , R Biran, K E Rudd, J S Parkinson
Affiliations

A signal transducer for aerotaxis in Escherichia coli

S I Bibikov et al. J Bacteriol. 1997 Jun.

Abstract

The newly discovered aer locus of Escherichia coli encodes a 506-residue protein with an N terminus that resembles the NifL aerosensor and a C terminus that resembles the flagellar signaling domain of methyl-accepting chemoreceptors. Deletion mutants lacking a functional Aer protein failed to congregate around air bubbles or follow oxygen gradients in soft agar plates. Membranes with overexpressed Aer protein also contained high levels of noncovalently associated flavin adenine dinucleotide (FAD). We propose that Aer is a flavoprotein that mediates positive aerotactic responses in E. coli. Aer may use its FAD prosthetic group as a cellular redox sensor to monitor environmental oxygen levels.

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References

    1. Nature. 1991 Mar 14;350(6314):170-2 - PubMed
    1. J Bacteriol. 1989 Sep;171(9):4617-22 - PubMed
    1. Mol Microbiol. 1993 Aug;9(4):869-79 - PubMed
    1. J Bacteriol. 1994 Jan;176(2):344-50 - PubMed
    1. Proc Natl Acad Sci U S A. 1994 Jun 7;91(12):5485-9 - PubMed

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