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Review
. 1997 Jun;77(3):509-28.
doi: 10.1016/s0039-6109(05)70566-1.

General principles of wound healing

M B Witte  1 , A Barbul
Affiliations
Review

General principles of wound healing

M B Witte et al. Surg Clin North Am. 1997 Jun.

Abstract

Wound healing is a complex process involving different biologic and immunologic systems. Despite improvements in diagnostics and therapy, wound failures remain a clinical problem. The approach to a nonhealed wound is an interdisciplinary challenge that should not be underestimated. Better understanding of the complex wound-healing cascade helps our approach to wound healing and its possible failure. Manipulations of the involved immunologic features offer future therapeutic strategies.

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