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. 1997 Jun;45(4):719-23.
doi: 10.1016/s0031-9422(97)00028-9.

Bioactive annonaceous acetogenins from Rollinia mucosa

G Shi  1 , J M MacDougal, J L McLaughlin
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Bioactive annonaceous acetogenins from Rollinia mucosa

G Shi et al. Phytochemistry. 1997 Jun.

Abstract

Two new bioactive Annonaceous acetogenins, rollitacin (1) and rollinacin (2), along with one known acetogenin, javoricin, were isolated from the ethanolic extract of the leaves of Rollinia mucosa. Compounds 1 and 2 exhibited selective inhibitory effects among six human solid tumour cell lines. The structural elucidations of 1 and 2 were achieved by various spectroscopic analyses and chemical derivatizations.

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