Specificity of the antibody response of rabbits to a self-antigen
- PMID: 91974
- DOI: 10.1038/282468a0
Specificity of the antibody response of rabbits to a self-antigen
Abstract
The demonstration that the antigenic determinants on rabbit cytochrome c that elicit antibodies in rabbits occur in regions of variability among mammalian cytochromes c suggests the existence of an evolutionary process which eliminates genetic specificities for self-determinants.
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