Comment on

• HIV infection induces changes in CD4+ T-cell phenotype and depletions within the CD4+ T-cell repertoire that are not immediately restored by antiviral or immune-based therapies.

  Connors M, Kovacs JA, Krevat S, Gea-Banacloche JC, Sneller MC, Flanigan M, Metcalf JA, Walker RE, Falloon J, Baseler M, Feuerstein I, Masur H, Lane HC. Connors M, et al. Nat Med. 1997 May;3(5):533-40. doi: 10.1038/nm0597-533. Nat Med. 1997. PMID: 9142122