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. 1977 Oct;12(4):513-7.
doi: 10.1128/AAC.12.4.513.

Plasmid-mediated resistance to gentamicin in Staphylococcus aureus

D O Wood, M J Carter, G K Best

Plasmid-mediated resistance to gentamicin in Staphylococcus aureus

D O Wood et al. Antimicrob Agents Chemother. 1977 Oct.

Abstract

Two strains isolated from a recent outbreak of infections by gentamicin-resistant Staphylococcus aureus were examined to determine whether genetic control of this resistance is plasmid or chromosomally mediated. Curing techniques indicated a plasmid location in both strains. Physical isolation and characterization of the plasmid deoxyribonucleic acid from one strain revealed that the determinant for gentamicin resistance resides on a 50S plasmid.

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References

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