Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1997 Jul 14;138(1):1-4.
doi: 10.1083/jcb.138.1.1.

Membrane dynamics at the endoplasmic reticulum-Golgi interface

S I Bannykh  1 , W E Balch
Affiliations
Review

Membrane dynamics at the endoplasmic reticulum-Golgi interface

S I Bannykh et al. J Cell Biol. .
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Morphological organization of ER export. A diagram summarizing the three tiers of organization of ER export complexes. An individual ER cisterna contains a collection of closely opposed buds that define a local transitional region (light zone with stippled COPII coated buds [Tier I]). A collection of Tier I budding sites (cylindrical region outlined by dashed lines forming Tier II) encompass a central cavity containing a collection of tubular elements (VTCs) that have COPI coats (dense coated buds). Tier III defines the entire export complex consisting of a local concentration of ER budding sites and the central VTC. See cover for a morphological rendering of a typical export complex. Figure taken from reference .
Figure 2
Figure 2
Potential models for transport of cargo through the Golgi stack. (A) The first model illustrates that movement of cargo between the ER, VTC/CGN, and individual cisternae of the Golgi stack requires distinct vesicular carriers at each step. Recycling between stacks is mediated by the COPI machinery. (B) The second model envisions that COPII vesicles fuse to form VTC/CGN, which subsequently assemble to form the first stack. Cargo does not exit the CGN; rather, COPI recycling vesicles harboring Golgi processing enzymes direct its maturation to transform it into the trans-most cisternae. New VTCs continuously replenish the cis face.
See this image and copyright information in PMC

References

    1. Aridor M, Balch WE. Principles of selective transport: coat complexes hold the key. Trends Cell Biol. 1996;6:315–320. - PubMed
    1. Aridor M, Bannykh SI, Rowe T, Balch WE. Sequential coupling between COPII and COPI vesicle coats in endoplasmic reticulum to Golgi transport. J Cell Biol. 1995;131:875–893. - PMC - PubMed
    1. Balch WE, McCaffery JM, Plutner H, Farquhar MG. Vesicular stomatitis virus glycoprotein is sorted and concentrated during export from the endoplasmic reticulum. Cell. 1994;76:841–852. - PubMed
    1. Bannykh SI, Rowe T, Balch WE. Organization of endoplasmic reticulum export complexes. J Cell Biol. 1996;135:19–35. - PMC - PubMed
    1. Barlowe C, Orci L, Yeung T, Hosobuchi M, Hamamoto S, Salama N, Rexach MF, Ravazzola M, Amherdt M, Schekman R. COPII: a membrane coat formed by sec proteins that drive vesicle budding from the endoplasmic reticulum. Cell. 1994;77:895–907. - PubMed