Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 1997 Jul;20(7):662-4.
doi: 10.1002/clc.4960200715.

Propafenone-induced drug fever in the absence of agranulocytosis

D J O'Rourke  1 , R T Palac, P T Holzberger, B R Gerling, M L Greenberg
Affiliations
Case Reports

Propafenone-induced drug fever in the absence of agranulocytosis

D J O'Rourke et al. Clin Cardiol. 1997 Jul.

Abstract

Propafenone is an antiarrhythmic drug used in the treatment of life-threatening ventricular tachyarrhythmias. Adverse reactions necessitating discontinuation of the medication are common. Propafenone-induced drug fever has not been definitively proven. We present a case report of drug fever secondary to propafenone, confirmed with rechallenge.

PubMed Disclaimer

References

    1. Physicians' Desk Reference, 50th edition, p. 1352–1355. Montvale, NJ: Medical Economics Company, 1996.
    1. Echt DS, Liebson PR, Mitchell LB, Peters RW, Obias‐Mano D, Barker AH, Arensberg D, Baker A, Friedman L, Greene HL, Huther ML, Richardson DW, and the CAST Investigators : Mortality and morbidity in patients receiving encainide, flecanide or placebo. The Cardiac Arrhythmia Suppression Trial. N Engl J Med 1991; 324: 781–788 - PubMed
    1. The Cardiac Arrhythmia Suppression Trial II Investigators : Effect of the antiarrhythmic agent moricizine on survival after myocardial infarction. N Engl J Med 1992; 327: 227–233 - PubMed
    1. Reynolds JEF. (Ed): Martindale: The Extra Pharmacopoeia. 31st edition, p. 935–936. London: Pharmaceutical Press, 1996.
    1. Bryson HM, Palmer KJ, Langtry HD, Fitton A: Propafenone: A reappraisal of its pharmacology, pharmacokinetics and therapeutic use in cardiac arrhythmias. Drugs 1993; 45: 85–130 - PubMed

Publication types