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. 1997 May-Jun;42(3):215-8.

Effect of two anti-estrogens, clomiphene citrate and tamoxifen, on cervical mucus and sperm-cervical mucus interaction

V Annapurna  1 , L K Dhaliwal, S Gopalan
Affiliations
  • PMID: 9222807

Effect of two anti-estrogens, clomiphene citrate and tamoxifen, on cervical mucus and sperm-cervical mucus interaction

V Annapurna et al. Int J Fertil Womens Med. 1997 May-Jun.

Abstract

Objective: To compare the effect of two ovulation-inducing agents, clomiphene citrate and tamoxifen, on cervical mucus and sperm-cervical mucus interaction.

Subjects and setting: Forty couples with unexplained infertility attending infertility clinic.

Methods: Cervical mucus scoring and postcoital test done using the Moghissi system in a spontaneous cycle (control cycle) and with clomiphene citrate or tamoxifen (study cycles).

Results: Clomiphene citrate significantly decreased cervical mucus production, whereas tamoxifen significantly improved the total score.

Conclusion: Tamoxifen is a better drug than clomiphene for ovulation induction in women with poor cervical mucus quality.

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