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. 1977 Oct 15;2(6093):989-91.
doi: 10.1136/bmj.2.6093.989.

Association of polymyalgia rheumatica and giant-cell arteritis with HLA-B8

B Hazleman, A Goldstone, D Voak

Association of polymyalgia rheumatica and giant-cell arteritis with HLA-B8

B Hazleman et al. Br Med J. .

Abstract

Histocompatibility antigens were determined in 30 patients with temporal arteritis, 27 patients with polymyalgia rheumatica, and 216 normal blood donors. HLA-B8 was significantly more common in patients with polymyalgia rheumatica (59%) and temporal arteritis (50%) than in the controls (27%). The findings of HLA-A10 in 26% of the patients with polymyalgia rheumatica compared with only 10% of the controls may be associated with the suggested immunological pathogenesis of the condition.

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