doi: 10.1111/j.1574-6968.1997.tb12560.x.
GAP1 activity is dependent on cAMP in Saccharomyces cerevisiae
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- PMID: 9228744
- DOI: 10.1111/j.1574-6968.1997.tb12560.x
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GAP1 activity is dependent on cAMP in Saccharomyces cerevisiae
FEMS Microbiol Lett.
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Abstract
General amino acid permease (GAP1) activity was evaluated in adenylate cyclase-deficient Saccharomyces cerevisiae to determine the effect of cAMP levels on GAP1 activity. Lowering cAMP concentrations in the culture media led to a decrease in the initial rates of L-citrulline uptake. Kinetics of the amino acid transport system showed a partial loss of transport capacity, with no apparent modifications in permease affinity.
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