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Review
. 1997 Jul;5(7):288-93.
doi: 10.1016/S0966-842X(97)01061-5.

Origins and functions of the chlamydial inclusion

T Hackstadt  1 , E R Fischer, M A Scidmore, D D Rockey, R A Heinzen
Affiliations
Review

Origins and functions of the chlamydial inclusion

T Hackstadt et al. Trends Microbiol. 1997 Jul.

Abstract

Chlamydiae dissociate themselves from the endocytic pathway shortly after internalization by actively modifying the vacuole to become fusogenic with sphingomyelin-containing exocytic vesicles. Interaction with this secretory pathway appears to provide a pathogenic mechanism that allows chlamydiae to establish themselves in a site that is not destined to fuse with lysosomes.

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