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. 1977 Nov 15;33(11):1493-5.
doi: 10.1007/BF01918829.

Ultrastructural changes in dog thyroid follicular cells elicit by concanavalin A in vitro

J A Fernandez-Pol, J P Binette, M T Hays

Ultrastructural changes in dog thyroid follicular cells elicit by concanavalin A in vitro

J A Fernandez-Pol et al. Experientia. .

Abstract

Dog thyroid follicular cells exposed to concanavalin A (Con A) in vitro showed changes in cell shape, induction of colloid droplets and alterations in the distribution of microvilli. Cells exposed to Con A plus suboptimal concentrations of TSH (thyroid stimulating hormone) showed pseudopods and their cytoplasm was virtually occupied with colloid droplets. This findings suggest that Con A potentiated pseudopod and colloid droplet formation induced by TSH.

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