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. 1997;14(2):147-51.
doi: 10.1023/a:1007921418679.

Bovine rotavirus 993/83 shows a third subtype of avian VP7 protein

A Rohwedder  1 , H Hotop, N Minamoto, H Ito, O Nakagomi, H Brüssow
Affiliations

Bovine rotavirus 993/83 shows a third subtype of avian VP7 protein

A Rohwedder et al. Virus Genes. 1997.

Abstract

VP7 genes of rotavirus (RV) 993/83 isolated from a German calf with diarrhea and of RV PO-13 isolated from a Japanese pigeon were sequenced. Alignment of the deduced VP7 amino acid sequence showed 98.8% sequence identity, while only 70% and 84% identity was seen with VP7 from chicken RV Ch-2 and turkey RV Ty-1, respectively. Over the antigenic regions A, B, and C mammalian RV 993/83 showed more aa identity with mammalian G3 RVs than with chicken RV Ch-2, which could explain the strong one-way cross-neutralization observed between RV 993/83 and G3 RVs. Despite marked VP7 sequence diversity avian RVs could not be differentiated into distinct G types.

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