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Review
. 1997 May 30:820:56-73; discussion 73-4.
doi: 10.1111/j.1749-6632.1997.tb46189.x.

In vivo imaging of fatty acid incorporation into brain to examine signal transduction and neuroplasticity involving phospholipids

S I Rapoport  1 , D Purdon, H U Shetty, E Grange, Q Smith, C Jones, M C Chang
Affiliations
Review

In vivo imaging of fatty acid incorporation into brain to examine signal transduction and neuroplasticity involving phospholipids

S I Rapoport et al. Ann N Y Acad Sci. .

Abstract

An in vivo method is presented that allows quantification and imaging of fatty acid incorporation into different brain phospholipids in relation to membrane synthesis, neuroplasticity, and signal transduction. The method can be used with positron emission tomography, and may help to evaluate brain phospholipid metabolism in humans with brain tumors, neurodegenerative disease, cerebral ischemia or trauma, or neurotoxic effects of drugs or other agents.

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