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Review
. 1997 Jul 23:3:8.

Selenite nuclear cataract: review of the model

T R Shearer  1 , H Ma, C Fukiage, M Azuma
Affiliations
  • PMID: 9238097
Free article
Review

Selenite nuclear cataract: review of the model

T R Shearer et al. Mol Vis. .
Free article

Abstract

Selenite overdose cataract, an experimental model of nuclear cataract produced in young rats is reviewed. Topics include procedures for cataract production and assessment, metabolic and molecular changes in the epithelium of the lens, calcium accumulation, activation of calcium-activated protease system, mechanisms for crystallin precipitation, anti-cataract drug testing and relevance to human cataract.

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