Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1997 Aug;154(8):1051-6.
doi: 10.1176/ajp.154.8.1051.

An MRI study of the corpus callosum in autism

J Piven  1 , J Bailey, B J Ranson, S Arndt
Affiliations

An MRI study of the corpus callosum in autism

J Piven et al. Am J Psychiatry. 1997 Aug.

Abstract

Objective: The purpose of this study was to examine the size of subregions of the corpus callosum in autistic individuals.

Method: The areas of three subregions (anterior, body, and posterior) of the corpus callosum were examined on midsagittal magnetic resonance images of 35 autistic subjects whose mean age was 18 years and 36 healthy comparison subjects matched on age and IQ.

Results: After controlling for total brain volume, gender, and performance IQ, the authors detected a significantly smaller size of the body and posterior subregions of the corpus callosum in the autistic individuals.

Conclusions: In the context of recent reports of increased brain size in autism, several possible mechanisms are considered in exploring the significance of a smaller relative size of the corpus callosum in autism.

PubMed Disclaimer

Publication types

LinkOut - more resources