Biochemical correlates of individual behavior

Abstract

This article is a review of data (results of the authors' investigations and data from the literature) concerning neurochemical correlates of individual behavior in rats. The "emotional resonance" test was used for behavioral selection of rats. Individual behavior in this test is related to the differences in free radical-mediated processes, membrane lipid content, nitric oxide synthase activity, and cAMP pattern in cerebral macrostructures. Behavior-related differences may be revealed in intact animals; however, most of them are reactive (induced by significant external factors). These differences depend on age; they may be global, specific for selected brain regions, and/or related to interhemisphere lateralization of biochemical parameters.