doi: 10.1084/jem.146.5.1461.
Expression of a new cell surface antigen on activated murine macrophages
- PMID: 925608
- PMCID: PMC2180958
- DOI: 10.1084/jem.146.5.1461
Item in Clipboard
Expression of a new cell surface antigen on activated murine macrophages
J Exp Med.
.
Abstract
A macrophage cell-surface antigen associated with pyran and Corynebacterium parvum-activated macrophages and P388D1 cells but not detectable on normal or glycogen and thioglycollate-elicited murine macrophages has been described. The antigen was demonstrated both by complement-mediated cytotoxicity and immunofluorescence, using an appropriately absorbed rabbit antiserum to P388D1. This antiserum should enable the characterization of activated macrophage cell populations on an individual cell basis and should be a useful probe to study the interactions of macrophages with tumor cells and the relationship of activation to cell-surface changes.
Similar articles
-
Macrophage activation and mobilization in nude mice by Corynebacterium parvum and pyran: a functional and histologic study.J Surg Oncol. 1980;14(4):327-32. doi: 10.1002/jso.2930140406. J Surg Oncol. 1980. PMID: 6969333
-
Augmentation of specific macrophage-mediated cytotoxicity: correlations with agents which enhance antitumor resistance.Cell Immunol. 1976 Aug;25(2):309-16. doi: 10.1016/0008-8749(76)90121-0. Cell Immunol. 1976. PMID: 782731 No abstract available.
-
Relationship of expression of A cell-surface antigen on activated murine macrophages to tumor cell cytotoxicity.J Immunol. 1978 Jun;120(6):2080-5. J Immunol. 1978. PMID: 659893 No abstract available.
-
Functional heterogeneity in macrophages activated by Corynebacterium parvum: characterization of subpopulations with different activities in promoting immune responses and suppressing tumor cell growth.J Immunol. 1977 May;118(5):1530-40. J Immunol. 1977. PMID: 323353 Review.
-
Immunopharmacology of pyran copolymer.Pharmacol Res Commun. 1978 Jun;10(6):489-501. doi: 10.1016/s0031-6989(78)80048-4. Pharmacol Res Commun. 1978. PMID: 358211 Review. No abstract available.
Cited by
-
Anti-Mac-1 selectively inhibits the mouse and human type three complement receptor.J Exp Med. 1982 Oct 1;156(4):1000-9. doi: 10.1084/jem.156.4.1000. J Exp Med. 1982. PMID: 7153706 Free PMC article.
-
Establishment of a hybridoma secreting a monoclonal antibody specific for activated tumoricidal macrophages.J Exp Med. 1982 Oct 1;156(4):1286-91. doi: 10.1084/jem.156.4.1286. J Exp Med. 1982. PMID: 7153713 Free PMC article.
-
In vitro killing of Ehrlichia risticii by activated and immune mouse peritoneal macrophages.Infect Immun. 1993 Mar;61(3):861-7. doi: 10.1128/iai.61.3.861-867.1993. Infect Immun. 1993. PMID: 8432606 Free PMC article.
-
Natural and induced antisera specific for pulmonary macrophages.Lung. 1984;162(3):171-82. doi: 10.1007/BF02715645. Lung. 1984. PMID: 6381903 No abstract available.
-
Mechanisms of macrophage activation.Clin Exp Immunol. 1980 May;40(2):223-34. Clin Exp Immunol. 1980. PMID: 6254703 Free PMC article. Review. No abstract available.
