Establishment of a lymphoblastoid cell line and isolation of an Epstein-Barr-related virus of gorilla origin
- PMID: 92573
- PMCID: PMC353513
- DOI: 10.1128/JVI.31.3.845-848.1979
Establishment of a lymphoblastoid cell line and isolation of an Epstein-Barr-related virus of gorilla origin
Abstract
A B-lymphoid cell line was established from a normal gorilla. The cells contained Epstein-Barr virus-related antigens, and herpesvirus particles were demonstrated by electron microscopy. DNA-DNA reassociation kinétics revealed 30 to 40% hybridization to Epstein-Barr virus with 50 genomes per cell. Examination of the viral nuclear antigen with gorilla sera showed this to be a unique isolate termed Herpesvirus gorilla. H. gorilla transformed gibbon B-lymphocytes in vitro.
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