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. 1997 Aug;41(8):1835-6.
doi: 10.1128/AAC.41.8.1835.

In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds

M Del Poeta  1 , W A Schell, J R Perfect
Affiliations

In vitro antifungal activity of pneumocandin L-743,872 against a variety of clinically important molds

M Del Poeta et al. Antimicrob Agents Chemother. 1997 Aug.

Abstract

The in vitro activity of the new antifungal drug pneumocandin L-743,872 against 55 isolates of clinically important molds was examined by an adapted macrobroth dilution method for yeasts. Pneumocandin L-743,872 exhibited in vitro antifungal activity against Alternaria sp., Aspergillus flavus, Aspergillus fumigatus, Curvularia lunata, Exophiala jeanselmei, Fonsecaea pedrosoi, Paecilomyces variotii, and Scedosporium apiospermum. The drug appeared to lack significant in vitro inhibitory activity against Fusarium oxysporum, Fusarium solani, Rhizopus arrhizus, Paecilomyces lilacinus, and Scedosporium prolificans.

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References

    1. Antimicrob Agents Chemother. 1996 Sep;40(9):2106-10 - PubMed
    1. Antimicrob Agents Chemother. 1995 Feb;39(2):314-9 - PubMed