The promise and problems of meta-analysis

Comparative Study

J C Bailar 3rd. N Engl J Med. 1997.

. 1997 Aug 21;337(8):559-61.

doi: 10.1056/NEJM199708213370810.

No abstract available

Comment in

Meta-analyses and large randomized, controlled trials.
Song FJ, Sheldon TA. Song FJ, et al. N Engl J Med. 1998 Jan 1;338(1):60. N Engl J Med. 1998. PMID: 9424564 No abstract available.
Meta-analyses and large randomized, controlled trials.
Khan S, Williamson P, Sutton R. Khan S, et al. N Engl J Med. 1998 Jan 1;338(1):60-1; author reply 61-2. N Engl J Med. 1998. PMID: 9424566 No abstract available.
Meta-analyses and large randomized, controlled trials.
Stewart LA, Parmar MK, Tierney JF. Stewart LA, et al. N Engl J Med. 1998 Jan 1;338(1):61; author reply 61-2. N Engl J Med. 1998. PMID: 9424569 No abstract available.

Discrepancies between meta-analyses and subsequent large randomized, controlled trials.
LeLorier J, Grégoire G, Benhaddad A, Lapierre J, Derderian F. LeLorier J, et al. N Engl J Med. 1997 Aug 21;337(8):536-42. doi: 10.1056/NEJM199708213370806. N Engl J Med. 1997. PMID: 9262498