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. 1997 Sep;65(9):3936-8.
doi: 10.1128/iai.65.9.3936-3938.1997.

Allelic variation in Streptococcus pneumoniae autolysin (N-acetyl muramoyl-L-alanine amidase)

S H Gillespie  1 , T D McHugh, H Ayres, A Dickens, A Efstratiou, G C Whiting
Affiliations

Allelic variation in Streptococcus pneumoniae autolysin (N-acetyl muramoyl-L-alanine amidase)

S H Gillespie et al. Infect Immun. 1997 Sep.

Abstract

The lytA gene encoding the autolysin of Streptococcus pneumoniae may be a virulence determinant. Single-strand conformational polymorphism analysis demonstrated heterogenicity throughout the gene in clinical isolates and strains from the clonal serotypes 7 and 14. Sequence analysis of part of the choline-binding domain showed that in two isolates four amino acid substitutions occurred.

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References

    1. Microb Pathog. 1996 Aug;21(2):71-83 - PubMed
    1. J Infect Dis. 1996 Jan;173(1):128-35 - PubMed
    1. Biochem Biophys Res Commun. 1986 Jun 13;137(2):614-9 - PubMed
    1. Gene. 1986;43(3):265-72 - PubMed
    1. Am Rev Respir Dis. 1987 Apr;135(4):869-74 - PubMed

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