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Review
. 1997 Aug;44(4):953-72.
doi: 10.1016/s0031-3955(05)70539-3.

Rhabdomyosarcoma. Biology and treatment

A S Pappo  1 , D N Shapiro, W M Crist
Affiliations
Review

Rhabdomyosarcoma. Biology and treatment

A S Pappo et al. Pediatr Clin North Am. 1997 Aug.

Abstract

Rhabdomyosarcoma is the most common soft-tissue sarcoma of childhood. Recognition of specific genetic changes in the two most common subtypes of rhabdomyosarcoma has allowed better understanding of the pathogenesis of this disease. In addition, identification of prognostic factors and the use of risk-directed multimodal therapy have improved the outcome for these patients significantly, with cure rates approaching 70%.

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