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Case Reports
. 1977 Apr;133(4):271-8.

[Striato-nigral degeneration. Clinical and anatomic study of a case which responded favorably to L-Dopa]

[Article in French]
J R Feve, J M Mussini, J F Mathé, J M Cler, M F Nomballais
  • PMID: 929031
Case Reports

[Striato-nigral degeneration. Clinical and anatomic study of a case which responded favorably to L-Dopa]

[Article in French]
J R Feve et al. Rev Neurol (Paris). 1977 Apr.

Abstract

The authors have reported the case of a 65 year old woman followed for almost 4 years with an akineticrigid Parkinsonian syndrome which responded well to levodopa. Waning of response finally occurred and despite the addition of a peripheral dopa decarboxylase inhibitor the patient died suddenly. Autopsy examination revealed pure nigro-striatal degeneration without any additional pathology. The report deals primarily with purity of the Parkinsonian picture and especially with the conspicuous and prolonged effect of levodopa.

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