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. 1997 Sep;66(1):24-9.
doi: 10.1002/(sici)1096-9098(199709)66:1<24::aid-jso6>3.0.co;2-p.

Patterns of failure and long-term results in high-risk resected gastric cancer treated with postoperative radiotherapy with or without intraoperative electron boost

R Martínez-Monge  1 , F A Calvo, I Azinovic, J J Aristu, J L Hernández, F Pardo, P Fernández, J García-Foncillas, J Alvarez-Cienfuegos
Affiliations

Patterns of failure and long-term results in high-risk resected gastric cancer treated with postoperative radiotherapy with or without intraoperative electron boost

R Martínez-Monge et al. J Surg Oncol. 1997 Sep.

Abstract

Background: To evaluate the possible role of adjuvant radiotherapy in the management of high-risk resected gastric carcinoma.

Methods: From 1982 to 1993, 62 patients surgically resected of a primary gastric cancer with adverse pathological features (serosal and/or regional lymph node involvement) were treated with postoperative radiotherapy with (Group I) or without (Group II) intraoperative electron boost to the surgical bed and coeliac axis (IORT).

Results: After a median follow-up of 75.6 months (range 4-120+) for IORT patients and 91.2 months (range 6-149+) for non-IORT patients, overall relapse rates for Group I and Group II patients were 44.5% and 48.6% and local-regional relapse rates were 11.1% and 20%, respectively. Actuarial survival rates projected at the maximum follow-up were 41% and 38% in Groups I and II, respectively.

Conclusions: This retrospective analysis suggests a beneficial effect of adjuvant external radiotherapy in promoting local-regional control in high-risk resected gastric cancer.

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