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. 1977 Dec 10;107(49):1841-2.

[Study of glucagon secretion in patients with hemochromatosis]

[Article in French]
J J Gonvers, L Henchoz, J R Hofstetter, W A Muller
  • PMID: 929150

[Study of glucagon secretion in patients with hemochromatosis]

[Article in French]
J J Gonvers et al. Schweiz Med Wochenschr. .

Abstract

Diabetes in idiopathic hemochromatosis has been considered to be secondary to islet cell damage resulting from the iron deposits. Plasma glucagon was measured by immunoassay using the pancreas specific 30-K antiserum, and was found to be normal or slightly elevated during arginine-infusion tests in patients exhibiting both hemochromatosis and pathological glucose tolerance. This suggests that diabetes in hemochromatosis is not due to a lesion resulting from the iron deposits. The two affections appear to be merely associated and are possibly genetically linked.

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