Physical structure of the replication origin of bacteriophage lambda
- PMID: 929187
- DOI: 10.1126/science.929187
Physical structure of the replication origin of bacteriophage lambda
Abstract
The nucleotide sequence of part of the replication region of wild-type bacteriophage lambda and of four mutants defective in the origin of DNA replication (ori-) has been determined. Three of the ori- mutations are small deletions, and one is a transversion. The sequence of the origin region, defined by these mutations, contains a number of unusual features.
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