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Review
. 1997 Sep;5(9):343-9.
doi: 10.1016/S0966-842X(97)01099-8.

How Salmonella became a pathogen

E A Groisman  1 , H Ochman
Affiliations
Free article
Review

How Salmonella became a pathogen

E A Groisman et al. Trends Microbiol. 1997 Sep.
Free article

Abstract

In many pathogens, virulence can be conferred by a single region of the genome. In contrast, the facultative intracellular lifestyle of Salmonella demands a large number of genes distributed around the chromosome. The evolution of Salmonella has been marked by the acquisition of several 'pathogenicity islands', each contributing to the unique virulence properties of this microorganism.

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