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. 1997 Sep;96(3):138-41.
doi: 10.1111/j.1600-0404.1997.tb00255.x.

A historical perspective on the mortality associated with chronic epilepsy

M F O'Donoghue  1 , J W Sander
Affiliations

A historical perspective on the mortality associated with chronic epilepsy

M F O'Donoghue et al. Acta Neurol Scand. 1997 Sep.

Abstract

Objective: To examine the secular trend in the mortality associated with chronic epilepsy.

Material and methods: Using data from the Chalfont Centre for Epilepsy, UK, a residential centre for people with epilepsy, we determined the standardized mortality ratio (SMR) in the Chalfont population for each 5-year epoch from 1896 to 1965.

Results: The SMR was found to be between 2 and 3 for most 5 year epochs from 1896 to 1965.

Conclusion: Changes in the average age and disability of the residents at the Chalfont Centre confound a definite conclusion, but the evidence suggests the possibility that an excess mortality has been associated with chronic epilepsy for 100 years despite major changes in treatment.

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