Malaria sporozoites and chylomicron remnants compete for binding sites in the liver
- PMID: 9303206
Malaria sporozoites and chylomicron remnants compete for binding sites in the liver
Abstract
Like Malaria sporozoites and the circumsporozoite protein, remnants of lipoproteins are rapidly cleared from the circulation and enter hepatocytes. Here we review the evidence that the same set of liver heparan sulfate proteoglycans are the initial binding sites of malaria sporozoites and the lipoprotein remnants.
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