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. 1997 Sep;41(9):2035-6.
doi: 10.1128/AAC.41.9.2035.

Synergistic activities of clarithromycin and pyrazinamide against Mycobacterium tuberculosis in human macrophages

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Synergistic activities of clarithromycin and pyrazinamide against Mycobacterium tuberculosis in human macrophages

N Mor et al. Antimicrob Agents Chemother. 1997 Sep.

Abstract

The combination of clarithromycin and pyrazinamide was found to be synergistic against Mycobacterium tuberculosis in human macrophages. MICs were four- to eightfold lower for this combination than they were for either drug alone. Clarithromycin and rifampin, however, had only an additive effect.

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