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. 1979 Dec 15;35(12):1060-1.
doi: 10.1007/BF01953254.

Epidermal growth factor stimulates proliferation of rat hepatoma cells producing alpha-fetoprotein

Y Kaneko, Y Imai, F Matsuzaki, Y Endo, T Oda

Epidermal growth factor stimulates proliferation of rat hepatoma cells producing alpha-fetoprotein

Y Kaneko et al. Experientia. .

Abstract

Epidermal growth factor stimulated both [3H]thymidine uptake and proliferation of rat AH66 hepatoma cells. However, the increase in cell number was not accompanied by a proportional increase in the levels of alpha-fetoprotein of the culture media. The effects of EGF on the cell proliferation were antagonized by N6,O2'-dibutyryl cAMP.

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References

    1. J Cell Biol. 1976 Oct;71(1):159-71 - PubMed
    1. Ann N Y Acad Sci. 1975 Aug 22;259:29-36 - PubMed
    1. Proc Natl Acad Sci U S A. 1976 Oct;73(10):3589-93 - PubMed
    1. Proc Natl Acad Sci U S A. 1973 Oct;70(10):2964-8 - PubMed
    1. Nature. 1977 Feb 3;265(5593):421-4 - PubMed