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Case Reports
. 1997;27(7):661-3.
doi: 10.1007/BF02388226.

Closure of a ventricular septal defect in a patient with von Willebrand disease

S Tatebe  1 , H Kanazawa, Y Yamazaki, E Aoki, Y Sakurai, H Miyamura
Affiliations
Case Reports

Closure of a ventricular septal defect in a patient with von Willebrand disease

S Tatebe et al. Surg Today. 1997.

Abstract

Few reports of open heart surgery being performed in patients with von Willebrand disease (vWD) have been documented. We describe herein the case of a 5-year-old girl with a ventricular septal defect (VSD) and vWD who underwent patch closure under cardiopulmonary bypass (CPB). The hematological parameters relating to vWD, namely, factor VIII, von Willebrand factor, and factor VIII-related antigen were monitored perioperatively. These laboratory findings were elevated after the termination of CPB, and consistently maintained within the normal range for 4 months postoperatively. The operation was successfully completed without the administration of factor VIII concentrates or homologous blood products.

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