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Review
. 1997 Sep;174(1-2):305-19.

Reactive oxygen species, mitochondria, apoptosis and aging

S Papa  1 , V P Skulachev
Affiliations
  • PMID: 9309704
Review

Reactive oxygen species, mitochondria, apoptosis and aging

S Papa et al. Mol Cell Biochem. 1997 Sep.

Abstract

In this paper, we shall review various antioxygen defense systems of the cell paying particular attention to those that prevent superoxide formation rather than scavenge already formed superoxide and its products. The role of uncoupled, decoupled and non-coupled respiration, mitochondrial pore, mitochondrion-linked apoptosis will be considered. Mitochondrial theory of aging will be regarded in context of reactive oxygen species-induced damage of mitochondrial DNA.

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References

    1. Eur J Biochem. 1994 Dec 15;226(3):1071-8 - PubMed
    1. FEBS Lett. 1991 Aug 19;288(1-2):179-82 - PubMed
    1. Nature. 1981 Apr 9;290(5806):457-65 - PubMed
    1. Biol Reprod. 1993 Oct;49(4):730-6 - PubMed
    1. Biochemistry. 1993 May 11;32(18):4962-7 - PubMed

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