Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1997 Oct;71(10):7220-6.
doi: 10.1128/JVI.71.10.7220-7226.1997.

Bluetongue virus VP6 protein binds ATP and exhibits an RNA-dependent ATPase function and a helicase activity that catalyze the unwinding of double-stranded RNA substrates

N Stäuber  1 , J Martinez-Costas, G Sutton, K Monastyrskaya, P Roy
Affiliations

Bluetongue virus VP6 protein binds ATP and exhibits an RNA-dependent ATPase function and a helicase activity that catalyze the unwinding of double-stranded RNA substrates

N Stäuber et al. J Virol. 1997 Oct.

Abstract

RNA-dependent ATPase and helicase activities have been identified associated with the purified VP6 protein of bluetongue virus, a member of the Orbivirus genus of double-stranded RNA (dsRNA; Reoviridae family) viruses. In addition, the protein has an ATP binding activity. RNA unwinding of duplexes occurred with both 3' and 5' overhang templates, as well as with blunt-ended dsRNA, an activity not previously identified in other viral helicases. Although little sequence similarity to other helicases was detected, certain similarities to motifs commonly attributed to such proteins were identified.

PubMed Disclaimer

References

    1. Cell. 1989 Jun 16;57(6):955-63 - PubMed
    1. J Virol. 1995 Feb;69(2):935-47 - PubMed
    1. J Biol Chem. 1993 Jun 5;268(16):11798-802 - PubMed
    1. J Virol. 1995 Jun;69(6):3542-8 - PubMed
    1. J Virol. 1996 Jul;70(7):4778-82 - PubMed

Publication types

MeSH terms

LinkOut - more resources