Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1977 Dec;12(6):673-7.
doi: 10.1128/AAC.12.6.673.

Antibiotic susceptibility of Chlamydia trachomatis

H J Blackman, C Yoneda, C R Dawson, J Schachter

Antibiotic susceptibility of Chlamydia trachomatis

H J Blackman et al. Antimicrob Agents Chemother. 1977 Dec.

Abstract

The antibiotic susceptibility of Chlamydia trachomatis isolates was determined in a tissue culture system. Representatives of all currently recognized serotypes of trachoma-inclusion conjunctivitis agents were tested. Tetracycline and erythromycin yielded similar results, with 1.0 mug/ml preventing chlamydial replication. Rifampin was the most active antibiotic, with 0.25 mug/ml completely suppressing inclusion formation of all strains. Fifty percent end points were usually achieved at one-fourth to one-eighth the 100% suppression level. Penicillin was not as effective, and the assays were often irregular. Antibiotic susceptibility of these chlamydiae was essentially the same, regardless of serotype, anatomic site infected, geographic origin, or antibiotic use in the community.

PubMed Disclaimer

References

    1. Adv Pharmacol. 1969;7:253-82 - PubMed
    1. Nature. 1973 Jul 20;244(5412):173-4 - PubMed
    1. Antimicrob Agents Chemother. 1972 Sep;2(3):242-4 - PubMed
    1. Am J Ophthalmol. 1975 May;79(5):803-11 - PubMed
    1. J Antimicrob Chemother. 1976 Mar;2(1):71-6 - PubMed

MeSH terms

LinkOut - more resources