Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1997 Sep;87(9):1551-4.
doi: 10.2105/ajph.87.9.1551.

Aplastic anemia in rural Thailand: its association with grain farming and agricultural pesticide exposure. Aplastic Anemia Study Group

S Issaragrisil  1 , K Chansung, D W Kaufman, J Sirijirachai, T Thamprasit, N S Young
Affiliations

Aplastic anemia in rural Thailand: its association with grain farming and agricultural pesticide exposure. Aplastic Anemia Study Group

S Issaragrisil et al. Am J Public Health. 1997 Sep.

Abstract

Objectives: A population-based case-control study was conducted to elucidate the incidence and etiology of aplastic anemia in Thailand.

Methods: Case patients and hospital control patients were enrolled in three regions from 1989 to 1994; data were collected by interview.

Results: Forty-six percent of 81 case patients and 19% of 295 control patients from Khonkaen were grain farmers (estimated relative risk [RR] = 2.7, 95% confidence interval [CI] = 1.4, 5.2). Sixteen percent of case patients and 6% of control patients used agricultural pesticides (estimated RR = 2.7, 95% CI = 1.1, 6.6). The association with grain farming remained among those not exposed to pesticides. In Songkla, 16% of 43 case patients and 2% of 181 control patients were grain farmers (crude RR estimate = 11, 95% CI = 3.4, 35).

Conclusions: The relation of aplastic anemia to grain farming may partly explain the high incidence of aplastic anemia in Thailand.

PubMed Disclaimer

References

    1. Semin Hematol. 1973 Jul;10(3):195-223 - PubMed
    1. Am J Epidemiol. 1974 May;99(5):325-32 - PubMed
    1. Br J Haematol. 1995 Sep;91(1):80-4 - PubMed
    1. Blood. 1991 May 15;77(10):2166-8 - PubMed
    1. Q J Med. 1990 Mar;74(275):289-301 - PubMed

Publication types