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Case Reports
. 1997 Jul-Sep;32(3):257-64.
doi: 10.1007/BF02688623.

Tic douloureux, Parkinson's disease and the herpes connection

J S Howard 3rd  1
Affiliations
Case Reports

Tic douloureux, Parkinson's disease and the herpes connection

J S Howard 3rd. Integr Physiol Behav Sci. 1997 Jul-Sep.

Abstract

Several cases encountered in psychiatric practice are described in which herpetic involvement of the trigeminal nerve appeared to be crucial to the pathophysiology of the patient's illness. A brief history of herpes is discussed in terms of the anatomy and physiology of the trigeminal nerve. Particular attention is given to the effects of intraneuronal herpes on gasserian ganglion and spinal nuclei discharge thresholds, as well as viral pathways directly impacting the substantia nigra. Evidence characterizing Parkinson's disease as one of several important manifestations of CNS herpes is covered.

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References

    1. Mov Disord. 1993 Apr;8(2):233-4 - PubMed
    1. Brain Res. 1980 May 12;189(2):544-9 - PubMed
    1. Arch Neurol. 1996 Feb;53(2):125-33 - PubMed
    1. Antiviral Res. 1995 Jun;27(3):255-61 - PubMed
    1. Brain Res Bull. 1991 Feb;26(2):293-300 - PubMed

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