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Review
. 1997 Oct;10(5):436-42.
doi: 10.1097/00019052-199710000-00014.

Functions of dystrophin and dystrophin associated proteins

M Michalak  1 , M Opas
Affiliations
Review

Functions of dystrophin and dystrophin associated proteins

M Michalak et al. Curr Opin Neurol. 1997 Oct.

Abstract

Dystrophin is a protein product of the X-linked gene mutation that is responsible for Duchenne and Becker muscular dystrophies. The protein binds actin and associates with dystrophin-glycoprotein complex to link the cytoskeleton to the extracellular matrix. Defects in the components of the dystrophin-glycoprotein complex are responsible for several phenotypes of muscular dystrophy.

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