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. 1976 Apr;13(2):103-22.
doi: 10.1136/jmg.13.2.103.

Classification and relationships of induced chromosomal structual changes

J R Savage

Classification and relationships of induced chromosomal structual changes

J R Savage. J Med Genet. 1976 Apr.

Abstract

A detailed survey is given of the types and classification of primary structural changes that can be induced in chromosomes and observed at the first metaphase after the initial damage. Comments upon identification and scoring are given for the benefit of new workers. The annotation concludes with a brief discussion of the potential relationships between the primary types, and the secondary or derived types encountered in clinical studies.

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