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. 1997 Oct;3(10):1076-8.
doi: 10.1038/nm1097-1076.

Gastrogenomic delights: a movable feast

J A Eisen, D Kaiser, R M Myers

Gastrogenomic delights: a movable feast

J A Eisen et al. Nat Med. 1997 Oct.
No abstract available

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Figures

Figure 1
Figure 1
Transmission electron micrographs of H. pylori (left) and E. coli (right).
Figure 2
Figure 2
Reconstruction of the evolution of MutS-like proteins in bacteria using molecular phylogenetics. MutS-like protein sequences were aligned and a tree of these sequences was generated using molecular phylogenetic methods (details are available from the authors on request). left, The tree of MutS-like proteins (thin lines) is shown embedded within the species tree (thick grey lines). The gene duplication event (marked by an asterisk) occurred prior to the divergence of these bacterial species and led to the presence of two paralogous MutS-like subgroups (distinguished by different colors and gene subscripts a or b). Gene loss in some lineages is indicated when the MutS tree stops within the species tree. right, The MutS tree is extracted from the species tree and untwisted to better show the relaitonships among the different MutS forms. Only one lineage (labeled in blue) includes genes with established roles in mismatch repair. The genes in the second lineage (in red) have no known function. Because the H. pylori gene is a member of this second lineage, it should not be assigned the MutS function.
See this image and copyright information in PMC

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